Healthy glia
Microglia are a type of immune cell in the brain. They help protect the Brain by cleaning up debris and fighting infections.
Oligodendrocytes are cells in the Brain and Spinal Cord that provide support to Neurons. They create a protective coating called myelin, which helps speed up the electrical signals sent by Neurons.
Astrocytes are star-shaped cells in the Brain that help support and protect Neurons. They provide nutrients, maintain the right balance of chemicals, and help repair damage in the Brain.
Diseased glia
Frontotemporal Demensia
Frontotemporal Dementia (FTD) is a Brain disorder that affects a person's behavior, language, and personality. It's caused by damage to the front and side parts of the Brain, called the frontal and temporal lobes.
Multiple sclerosis
Multiple Sclerosis (MS) is a disease that affects the nervous system and is related to the function of Oligodendrocytes. In MS, the immune system mistakenly attacks myelin, causing communication problems between Neurons.
Hepatic encephalopathy
Hepatic Encephalopathy is a Brain problem related to Liver disease and Astrocyte function. When the Liver doesn't work well, harmful substances build up in the blood, causing Astrocytes to swell and affecting Brain function.
glia Treatment
FTD -> Microglia
Supportive care treats Frontotemporal Dementia by helping patients manage their symptoms and improve their quality of life. This may include therapy, medication, and assistance with daily activities.
multiple sclerosis -> oligodendrocyte
Natalizumab treats Multiple Sclerosis by blocking immune cells from entering the Brain and Spinal cord. This helps reduce inflammation and prevent further damage to myelin.
hepatic encephalopathy -> astrocyte
Lactulose treats Hepatic Encephalopathy by helping the body remove harmful substances from the blood. It works as a laxative, helping to eliminate toxins through the digestive system.

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