Healthy Granulocyte
Mast Cell
Mast Cells are a type of white blood cell found in our body's tissues, like the skin and mucous membranes. They play a role in allergy and inflammation by releasing chemicals like histamine when they encounter an allergen.
Basophil
Basophils are a type of white blood cell that also plays a role in allergic reactions. Like Mast Cells, they release histamine and other chemicals that cause inflammation and allergy symptoms.
Eosinophil
Eosinophils are another type of white blood cell that helps our body fight infections, especially parasitic ones, and plays a role in allergic reactions and inflammation.
Neutrophil
Neutrophils are the most common type of white blood cell and are an essential part of our immune system. They help fight infections by engulfing and destroying harmful bacteria and other foreign substances.
Diseased Granulocyte
Anaphylaxis
Anaphylaxis is a severe, life-threatening allergic reaction that occurs when Mast Cells release large amounts of histamine and other chemicals. This can cause symptoms like difficulty breathing, low blood pressure, and rapid heartbeat.
Allergic Rhinitis
Allergic Rhinitis, also known as hay fever, is caused by an allergic reaction to substances like pollen or dust mites. Histamine released by Basophils causes inflammation in the nasal passages, leading to symptoms like sneezing, itching, and a runny nose.
Eczema
Eczema is a skin condition characterized by red, itchy, and inflamed skin. Eosinophils are involved in the inflammation process, contributing to the symptoms of Eczema.
Deep Vein Thrombosis
Deep Vein Thrombosis (DVT) is a blood clot that forms in a deep vein, usually in the leg. Neutrophil activation can contribute to the formation of these blood clots by promoting inflammation and blood clotting.
Granulocyte Treatment
Anaphylaxis -> Mast cell
Epinephrine treats Anaphylaxis by quickly reversing the severe symptoms of the allergic reaction. It helps to open up the airways, increase blood pressure, and reduce swelling, giving the person a chance to recover.
Allergic Rhinitis -> Basophil
Fluticasone treats Allergic Rhinitis by reducing inflammation in the nasal passages. It is a corticosteroid medication that works by suppressing the immune system's response to allergens, which helps relieve symptoms like sneezing, itching, and a runny nose.
Eczema -> Eosinophil
Dupilumab treats Eczema by targeting specific proteins involved in the inflammation process, such as the cytokines IL-4/IL-13. This medication helps to reduce itching, redness, and skin irritation by blocking the action of these proteins.
DVT -> Neutrophil
Apixaban treats Deep Vein Thrombosis by preventing blood clots from forming or growing larger. It is an anticoagulant, or blood thinner, that works by blocking the action of the clotting protein, Factor Xa, which helps to keep the blood flowing smoothly and reduces the risk of complications.
