Myofibrils are a small part of a Muscle Fiber that helps muscles contract. They are made up of repeating units called sarcomeres, which contain proteins called actin and myosin. When these proteins interact, they pull the sarcomeres closer together, causing Myofibrils and the muscle to contract.
Muscle Fibers are long, thin cells that make up our muscles and help us move. These fibers contract, or shorten, when our brain sends signals, allowing us to perform various actions.
Skeletal Muscles are the muscles that attach to our bones and help us move our body. There have two main muscle fiber types: slow-twitch fibers for endurance and fast-twitch fibers for strength and speed. When our brain sends signals, these muscles contract, allowing us to perform actions like walking, running, or lifting objects.
Myasthenia Gravis is an autoimmune disease that causes muscle weakness. This happens because the body's immune system mistakenly attacks the communication between nerves and muscles (nicotinic receptors), making it hard for the muscles to contract properly and leading to difficulties in moving, speaking, or even breathing.
Epilepsy is a neurological disorder that causes sudden, uncontrolled bursts of electrical activity in the brain, leading to seizures. These seizures can result in a variety of symptoms, such as muscle spasms, loss of consciousness, or strange sensations, and they can vary in severity and duration.
Rhabdomyolysis is a serious condition where muscle tissue breaks down and releases a protein called myoglobin into the bloodstream. This can happen because of injury, extreme exercise, or other severe depletion of energy. Myoglobin can harm the kidneys and even lead to kidney failure if not treated quickly.
Myasthenia gravis -> Myofibril
Pyridostigmine treats Myasthenia Gravis by helping improve communication between nerves and muscles. This medication blocks the enzyme AChE which breaks down a chemical called acetylcholine, which is important for muscle movement, making it easier for the muscles to work properly.
epilepsy -> muscle fiber
Lamotrigine treats Epilepsy by helping to stabilize the electrical activity in the brain. It works by inhibiting sodium channels which reduces the number of abnormal electrical signals that can cause seizures and helps to control and prevent these episodes from happening.
rhabdomyolysis -> muscle
Isotonic saline treats Rhabdomyolysis by helping the body flush out harmful substances. Rhabdomyolysis is a condition where muscle tissue breaks down, releasing a protein called myoglobin into the bloodstream. Isotonic saline helps dilute and remove myoglobin from the blood, which can prevent kidney damage and other complications.